Annals of Diagnostic Pathology
Volume 10, Issue 1 , Pages 28-31 , February 2006

Primary hepatic neuroendocrine carcinoma: an underdiagnosed entity

  • Raymund Dala, MD

      Affiliations

    • Arkadi M. Rywlin MD Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 305 674 2277; fax: +1 305 674 2999.
    • ,
  • John Shoosmith, MD

      Affiliations

    • Department of Radiology, Mount Sinai Medical Center, Miami Beach, FL 33140, USA
    • ,
  • Rogerio Lilenbaum, MD

      Affiliations

    • Department of Hematology and Oncology, Mount Sinai Medical Center, Miami Beach, FL 33140, USA
    • ,
  • Beria Cabello-Inchausti, MD

      Affiliations

    • Arkadi M. Rywlin MD Department of Pathology and Laboratory Medicine, Mount Sinai Medical Center, Miami Beach, FL 33140, USA

References 

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  2. Pilichowska M, Kimura N, Ouchi A, et al. Primary hepatic carcinoid and neuroendocrine carcinoma: clinicopathological and immunohistochemical study of five cases. Pathol Int. 1999;49(4):318–324
  3. Iimuro Y, Deguchi Y, Ueda Y, et al. Primary hepatic carcinoid tumor with metachronous lymph node metastasis after long-term follow up. J Gastroenterol Hepatol. 2002;17(10):1119–1124
  4. Kaya G, Pasche C, Osterheld MC, et al. Primary neuroendocrine carcinoma of the liver: an autopsy case. Pathol Int. 2001;51(11):874–878
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  6. Walter JF, Appelman HD, Reuter SR. Angiographic and pathologic features of probable primary carcinoid-like hepatic tumors. Gastrointest Radiol. 1978;3:397–400
  7. Sioutos N, Virta S, Kessimian N. Primary hepatic carcinoid tumor: an electron microscopic and immunohistochemical study. Am J Clin Pathol. 1991;95(2):172–175
  8. Capella C, Heitz PU, Hofler H, et al. Revised classification of neuroendocrine tumors of the lung, pancreas and gut. Digestion. 1994;55(Suppl 3):11–23
  9. Craig JR, Peters RL, Edmondson HA. In: Atlas of tumor pathology, Second Series Fascicle 26: tumors of the liver and intrahepatic bile ducts. Washington (DC): Armed Forces Institute of Pathology; 1989;p. 108–112
  10. Ishak KG, Goodman ZD, Stocker JT. In: Atlas of tumor pathology, Third Series Fascicle 31: tumors of the liver and intrahepatic bile ducts. Washington (DC): Armed Forces Institute of Pathology; 2001;p. 274–275
  11. In:  Sternberg SS editors. Histology for pathologists. 2nd ed.. Philadelphia (Pa): Lippincott-Raven; 1997;p. 1133–1151
  12. Wilander E, Portela-Gomes G, Grimelius L, et al. Argentaffin and argyrophil reactions of human gastrointestinal carcinoids. Gastroenterology. 1977;73:733–736
  13. DeLellis RA. The neuroendocrine system and its tumors: an overview. Am J Clin Pathol. 2001;115(Suppl 1):S5–S16
  14. Wick MR. Neuroendocrine neoplasia. Am J Clin Pathol. 2000;113:331–335
  15. Ferrero A, Gallino C, D'Aloisio G, et al. Primary neuroendocrine carcinoma of the liver: difficult diagnosis of a rare neoplasm. Acta Chir Belg. 1999;99(6):299–302
  16. Anderson CJ, Dehdashti F, Cutler PD, et al. 64Cu-TETA-octreotide as a PET agent for patients with neuroendocrine tumors. J Nucl Med. 2001;42(2):213–221
  17. Chatal JF, LeBodic MF, Kraeber-Bodere F, et al. Nuclear medicine applications for neuroendocrine tumors. World J Surg. 2000;24:1285–1289
  18. McStay MK, Caplin ME. Carcinoid tumour. Minerva Med. 2002;93(5):389–401

PII: S1092-9134(05)00045-6

doi: 10.1016/j.anndiagpath.2005.04.013

Annals of Diagnostic Pathology
Volume 10, Issue 1 , Pages 28-31 , February 2006

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