Annals of Diagnostic Pathology
Volume 10, Issue 3 , Pages 157-159, June 2006

Collision sebaceous and basal cell carcinomas of the eyelid

  • Jaime Levy, MD

      Affiliations

    • Department of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva 84101, Israel
    • Corresponding Author InformationCorresponding author. Tel.: +972 8 640 0379; fax: +972 8 640 3927.
  • ,
  • Emanuela Cagnano, MD

      Affiliations

    • Pathology Institute, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel
  • ,
  • Daniel Benharroch, MD

      Affiliations

    • Pathology Institute, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva, Israel
  • ,
  • Tova Monos, MD

      Affiliations

    • Department of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva 84101, Israel
  • ,
  • Tova Lifshitz, MD

      Affiliations

    • Department of Ophthalmology, Soroka University Medical Center, Ben-Gurion University of the Negev, P.O. Box 151, Beer-Sheva 84101, Israel

Abstract 

Objective

To report a rare case of collision sebaceous and basal cell carcinomas of the eyelid.

Design

Interventional case report.

Methods

An 80-year-old woman presented with a nodular lesion at the center of the left lower eyelid. Small ulceration and madarosis were also present.

Results

The patient underwent excisional biopsy with frozen section control. Histopathology showed mixed sebaceous as well as basal cell carcinoma with uninvolved surgical margins. Oncologic survey did not disclose any other lesion. At 6-month follow-up, there was no evidence of recurrence, new lesions, or metastasis.

Conclusion

Sebaceous and basal cell carcinomas can coexist in the eyelid within the same clinical lesion. Because of the potential risk of metastasis of sebaceous carcinoma, close follow-up of the patients is advisable.

Keywords: Eyelid, Sebaceous carcinoma, Basal cell carcinoma

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 The authors have no proprietary interest in any of the materials or techniques used in this study.

PII: S1092-9134(05)00124-3

doi:10.1016/j.anndiagpath.2005.07.018

Annals of Diagnostic Pathology
Volume 10, Issue 3 , Pages 157-159, June 2006