Annals of Diagnostic Pathology
Volume 10, Issue 5 , Pages 288-293 , October 2006

Ovarian Sertoli-Leydig cell tumor of intermediate grade with heterologous elements of rhabdomyosarcoma. A case report and a review of the literature

  • Anni Grove, MD

      Affiliations

    • Institute of Pathology, Aalborg University Hospital, DK-9000 Aalborg, Denmark
    • Corresponding Author InformationCorresponding author.
    • ,
  • Vibeke Vestergaard, MD

      Affiliations

    • Institute of Pathology, Hjørring Hospital, DK-9800 Hjørring, Denmark

References 

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  2. Roth LM, Anderson MC, Govan ADT, et al. Sertoli-Leydig cell tumors. A clinicopathologic study of 34 cases. Cancer. 1981;48:187–197
  3. Young RH, Scully RE. Ovarian Sertoli-Leydig cell tumors. A clinicopathological analysis of 207 cases. Am J Surg Pathol. 1985;9:543–569
  4. Young RH, Scully RE. Ovarian Sertoli-Leydig cell tumors with a retiform pattern: a problem in histopathologic diagnosis. A report of 25 cases. Am J Surg Pathol. 1983;7:755–771
  5. Talerman A. Ovarian Sertoli-Leydig cell tumor (androblastoma) with retiform pattern. A clinicopathologic study. Cancer. 1987;60:3056–3064
  6. Mooney EE, Nogales FF, Bergeron C, et al. Retiform Sertoli-Leydig cell tumours: clinical, morphological and immunohistochemical findings. Histopathology. 2002;41:110–117
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  8. Young RH, Perez-Atayde AR, Scully RE. Ovarian Sertoli-Leydig cell tumor with retiform and heterologous components. Report of a case with hepatocytic differentiation and elevated serum alpha-fetoprotein. Am J of Surg Pathol. 1984;8:709–718
  9. Young RH, Prat J, Scully RE. Ovarian Sertoli-Leydig cell tumors with heterologous elements. I. Gastrointestinal epithelium and carcinoid: a clinicopathologic analysis of thirty-six cases. Cancer. 1982;50:2448–2456
  10. Mooney EE, Nogales FF, Tavassoli FA. Hepatocytic differentiation in retiform Sertoli-Leydig cell tumors: distinguishing a heterologous element from Leydig cells. Hum Pathol. 1999;30:611–617
  11. Hammad A, Jasnosz KM, Olson PR. Expression of alpha-fetoprotein by ovarian Sertoli-Leydig cell tumors. Arch Pathol Lab Med. 1995;119:1075–1079
  12. Prat J, Young RH, Scully RE. Ovarian Sertoli-Leydig cell tumors with heterologous elements. II. Cartilage and skeletal muscle: a clinicopathologic analysis of twelve cases. Cancer. 1982;50:2465–2475
  13. Hughesdon PE, Fraser IT. Arrhenoblastoma of ovary. Case report and histological review. Acta Obstet Gynecol Scand. 1953;1(Suppl 4):32–78
  14. Reddick RL, Walton LA. Sertoli-Leydig cell tumor of the ovary with teratomatous differentiation. Clinicopathologic considerations. Cancer. 1982;50:1171–1176
  15. Latthe P, Shafi MI, Rollason TP. Recurrence of Sertoli-Leydig cell tumour in contralateral ovary. Case report and review of literature. Eur J Gynaecol Oncol. 2000;21:62–63
  16. Guérard MJ, Ferenczy A. Ovarian Sertoli-Leydig cell tumor with rhabdomyosarcoma: an ultrastructural study. Ultrastruct Pathol. 1982;3:347–358
  17. Kostopoulou E, Talerman A. Ovarian Sertoli-Leydig cell tumor of intermediate differentiation with immature skeletal muscle heterologous elements. Acta Obstet Gynecol Scand. 2003;82:197–198
  18. Schwartz PE, Price FV, Snyder MK. Management of ovarian stromal tumors. In:  Rubin SC,  Sutton GR editor. Ovarian Cancer 2001. 2nd ed.. Philadelphia: Lippincott Williams and Wilkins; 2001;p. 383–398
  19. Sebire NJ, Malone M. Myogenin and MyoD1 expression in paediatric rhabdomyosarcomas. J Clin Pathol. 2003;56:412–416

PII: S1092-9134(05)00166-8

doi: 10.1016/j.anndiagpath.2005.09.012

Annals of Diagnostic Pathology
Volume 10, Issue 5 , Pages 288-293 , October 2006

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