Annals of Diagnostic Pathology
Volume 10, Issue 6 , Pages 352-356 , December 2006

Diffuse intra-abdominal clear cell myomelanocytic tumor: report of an unusual presentation of “PEComatosis” simulating peritoneal mesothelioma

  • Tiziana Salviato, MD

      Affiliations

    • Department of Anatomic Pathology, City Hospital, I 35013 Cittadella, Italy
    • ,
  • Giuseppe Altavilla, MD

      Affiliations

    • Department of Anatomic Pathology, University of Padua School of Medicine, I 35100 Padua, Italy
    • ,
  • Graziella Busatto, ScD

      Affiliations

    • Department of Anatomic Pathology, City Hospital, I 35013 Cittadella, Italy
    • ,
  • Stefano Pizzolitto, MD

      Affiliations

    • Division of Anatomic Pathology, Department of Pathology and Laboratory Medicine, General Hospital “S. Maria della Misericordia”, I 33100 Udine, Italy
    • ,
  • Giovanni Falconieri, MD

      Affiliations

    • Division of Anatomic Pathology, Department of Pathology and Laboratory Medicine, General Hospital “S. Maria della Misericordia”, I 33100 Udine, Italy
    • Corresponding Author InformationCorresponding author. Tel.: +39 0432 552826; fax: +39 0432 552830.

References 

  1. Bonetti F, Pea M, Martignoni G, et al. PEC and sugar. Am J Surg Pathol. 1992;16:307–308
  2. Pea M, Martignoni G, Zamboni G, et al. Perivascular epithelioid cell. Am J Surg Pathol. 1996;20:1149–1153
  3. Folpe AL. Neoplasms with perivascular epithelioid cell differentiation. In:  Fletcher CDM,  Unni KK,  Mertens F editor. Tumours of soft tissue and bone. Lyon: IARC Press; 2002;p. 221–222
  4. Folpe AL, Goodman ZD, Ishak KG, et al. Clear cell myomelanocytic tumor of the falciform ligament/ligamentum teres: a novel member of the perivascular epithelioid clear cell family of tumors with a predilection for children and young adults. Am J Surg Pathol. 2000;24:1239–1246
  5. Dimmler A, Seitz G, Hohenberger W, et al. Late pulmonary metastasis in uterine PEComa. J Clin Pathol. 2003;56:627–628
  6. Lyengar P, DeAngelis DD, Greenberg M, et al. Perivascular epithelioid cell tumor of the orbit: a case report and review of the literature. Pediatr Dev Pathol. 2005;5:98–104
  7. Koutlas IG, Pambuccian SE, Jessurun J, et al. Perivascular epithelioid cell tumor of the oral mucosa. Arch Pathol Lab Med. 2005;129:690–693
  8. Pan CC, Yang AH, Chiang H. Malignant perivascular epithelioid cell tumor involving the prostate. Arch Pathol Lab Med. 2003;127:E96–E98
  9. Nadji M, Morales AR. Immunohistochemical techniques. In:  Silverberg SG editors. Principles and Practice of Surgical Pathology. New York (NY): Churchill Livingstone; 1990;p. 103–118
  10. Goldblum J, Hart WR. Localized and diffuse mesotheliomas of the genital tract and peritoneum in women. A clinicopathologic study of nineteen true mesothelial neoplasms, other than adenomatoid tumors, multicystic mesotheliomas, and localized fibrous tumors. Am J Surg Pathol. 1995;19:1124–1137
  11. Kerrigan SA, Turnnir RT, Clement PB, et al. Diffuse malignant epithelial mesotheliomas of the peritoneum in women: a clinicopathologic study of 25 patients. Cancer. 2002;94:378–385
  12. Shah IA, Salvatore JR, Kummet T, et al. Pseudomesotheliomatous carcinoma involving pleura and peritoneum: a clinicopathologic and immunohistochemical study of three cases. Ann Diagn Pathol. 1999;3:148–159
  13. Truong LD, Maccato ML, Awalt H, et al. Serous surface carcinoma of the peritoneum: a clinicopathologic study of 22 cases. Hum Pathol. 1990;21:99–110
  14. Fukunaga M, Naganuma H, Ushigome S, et al. Malignant solitary fibrous tumour of the peritoneum. Histopathology. 1996;28:463–466
  15. Young RH, Clement PB, McCaughey WT. Solitary fibrous tumors (‘fibrous mesotheliomas’) of the peritoneum. A report of three cases and a review of the literature. Arch Pathol Lab Med. 1990;114:493–495
  16. Bonetti F, Martignoni G, Colato C, et al. Abdominopelvic sarcoma of perivascular epithelioid cells. Report of four cases in young women, one with tuberous sclerosis. Mod Pathol. 2001;14:563–568
  17. Fadare O, Parkash V, Yilmaz Y, et al. Perivascular epithelioid cell tumor (PEComa) of the uterine cervix associated with intraabdominal “PEComatosis”: a clinicopathological study with comparative genomic hybridization analysis. World J Surg Oncol. 2004;2:35
  18. Nascimento AG, Keeney GL, Fletcher CD. Deciduoid peritoneal mesothelioma. An unusual phenotype affecting young females. Am J Surg Pathol. 1994;18:439–445
  19. Ordonez NG. Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas. Am J Surg Pathol. 1998;22:1203–1214
  20. Vang R, Kempson RL. Perivascular epithelioid cell tumor (‘PEComa’) of the uterus: a subset of HMB-45–positive epithelioid mesenchymal neoplasms with an uncertain relationship to pure smooth muscle tumors. Am J Surg Pathol. 2002;26:1–13
  21. Silva EG, Bodurka DC, Scouros MA, et al. A uterine leiomyosarcoma that became positive for HMB45 in the metastasis. Ann Diagn Pathol. 2005;9:43–45

PII: S1092-9134(05)00173-5

doi: 10.1016/j.anndiagpath.2005.09.019

Annals of Diagnostic Pathology
Volume 10, Issue 6 , Pages 352-356 , December 2006

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