Annals of Diagnostic Pathology
Volume 10, Issue 6 , Pages 363-366 , December 2006

Ewing sarcoma/primitive neuroectodermal tumor of the kidney: a case report. Diagnosed by immunohistochemistry and molecular analysis

  • Rakhee Saxena, MD

      Affiliations

    • Department of Surgical Pathology and Laboratory Medicine, Buffalo General Hospital, Buffalo, NY 14263, USA
  • ,
  • Sheila Sait, PhD

      Affiliations

    • Department of Surgical Pathology and Laboratory Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
  • ,
  • Paulette Mhawech-Fauceglia, MD

      Affiliations

    • Department of Surgical Pathology and Laboratory Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    • Corresponding Author InformationCorresponding author. Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. Tel.: +1 716 845 3204; fax: +1 716 845 3427.

References 

  1. Toskos M. Peripheral primitive neuroectodermal tumors: diagnosis, classification and prognosis. Perspect Pediatr Pathol. 1992;16:27–98
  2. Horowitz ME, Delaney TF, Malawer MM, Woo SY, Hicks MJ. Ewing's sarcoma of bone and soft tissue and peripheral primitive neuroectodermal tumor. In:  Pizzo PA,  Poplack PG editor. Principles and practice of pediatric oncology. Philadelphia: Lippincott; 1997;p. 831–863
  3. Rodriguez Galindo C, Marina NM, Fletcher BD, Parham DM, Bodner SM, Meyer WH. Is primitive neuroectodermal tumor of kidney a distinct entity?. Cancer. 1997;79:2243–2250
  4. Parham DM, Roloson GJ, Feely M, Green DM, Bridge JA, Beckwith JB. Primary malignant neuroepithelial tumors of the kidney: a clinicopathologic analysis of 146 adult and pediatric cases from the National Wilms' Tumor Study Group Pathology Center. Am J Surg Pathol. 2001;25:133–146
  5. Sheaff M, McManus A, Scheimberg I, Paris A, Shipley J, Baithun S. Primitive neuroectodermal tumor of the kidney confirmed by fluorescence in situ hybridization. Am J Surg pathol. 1997;21:461–468
  6. Premlata CS, Gayathri devi M, Biswas S, Mukherjee G, Balu S, Sundareshan TS, et al. Primitive neuroectodermal tumor of the kidney. A report of two cases diagnosed by fine needle aspiration cytology. Acta Cytol. 2003;47:475–479
  7. Folpe AL, Goldblum JR, Rubin BP, Shehata BM, Liu W, Dei T, et al. Morphologic and immunophenotypic diversity in Ewing family tumors: a study of 66 genetically confirmed cases. Am J Surg Pathol. 2005;8:1025–1033
  8. Folpe AL, Hill CE, Parham DM, O'Shea PA, Weiss SW. Immunohistochemical detection of FLI-1 protein expression. A study of 132 round cell tumors with emphasis on CD99-positive mimics of Ewing's sarcoma/primitive neuroectodermal tumor. Am J Surg Pathol. 2000;24:1657–1662
  9. Jimenez RE, Folpe AL, Lapham RL, Ro JY, O'Shea PA, Weiss SW, et al. Primary Ewing's sarcoma/primitive neuroectodermal tumor of the kidney. A clinicopathologic and immunohistochemical analysis of 11 cases. Am J Surg Pathol. 2002;26:320–327
  10. Stevenson AJ, Chatten J, Bertoni F, Miettinen M. CD99 (p30/32MIC2) neuroectodermal/Ewing's sarcoma antigen as an immunohistochemical marker: a review of more than 600 tumors and the literature experience. Appl Immunohistochem. 1994;2:231–240

PII: S1092-9134(05)00185-1

doi: 10.1016/j.anndiagpath.2005.11.001

Annals of Diagnostic Pathology
Volume 10, Issue 6 , Pages 363-366 , December 2006