Annals of Diagnostic Pathology
Volume 10, Issue 4 , Pages 222-229, August 2006

Soft tissue osteochondroma: case report and immunohistochemistry for parathyroid hormone–related protein

  • J. Robyn Ratcliff, MD

      Affiliations

    • Department of Orthopedic Surgery, Upstate Medical University, State University of New York at Syracuse, Syracuse, NY 13210, USA
    • ,
  • Asghar Naqvi, MD

      Affiliations

    • Department of Pathology, Upstate Medical University, State University of New York at Syracuse, Syracuse, NY 13210, USA
    • ,
  • Gustavo de la Roza, MD

      Affiliations

    • Department of Pathology, Upstate Medical University, State University of New York at Syracuse, Syracuse, NY 13210, USA
    • ,
  • Judith A. Strauss, BS

      Affiliations

    • Department of Orthopedic Surgery, Upstate Medical University, State University of New York at Syracuse, Syracuse, NY 13210, USA
    • ,
  • Timothy A. Damron, MD

      Affiliations

    • Department of Orthopedic Surgery, Upstate Medical University, State University of New York at Syracuse, Syracuse, NY 13210, USA
    • Corresponding Author InformationCorresponding author.

Abstract 

Surface lesions of bone usually present little diagnostic dilemma because the majority are conventional osteochondromas. Other surface bone lesions include periosteal chondroma, periosteal chondrosarcoma, and parosteal osteosarcoma. Mineralized soft tissue lesions such as myositis ossificans, synovial chondroma, and synovial sarcoma may present in a similar fashion when they occur in a juxtaarticular position. The soft tissue osteochondroma or paraarticular osteochondroma may simulate some of these more aggressive tumors, and its recognition is important to avoid overtreatment. A case of an 11-year-old male with a soft tissue osteochondroma is reported to illustrate the characteristic radiographic and histological features of this rare entity. No prior reports have examined soft tissue osteochondroma for expression of parathyroid hormone related protein, an established cartilage tumor proliferative mitogen.

Keywords: Osteochondroma, Soft tissue mass, PTHrP, Immunohistochemistry

To access this article, please choose from the options below

Login to an existing account or Register a new account.

  • Purchase this article for 31.50 USD (You must login/register to purchase this article)

    Online access for 24 hours. The PDF version can be downloaded as your permanent record.

  • Subscribe to this title

    Get unlimited online access to this article and all other articles in this title 24/7 for one year.

  • Claim access now

    For current subscribers with Society Membership or Account Number.

  • Visit SciVerse ScienceDirect to see if you have access via your institution.
 

PII: S1092-9134(05)00213-3

doi:10.1016/j.anndiagpath.2005.12.006

Annals of Diagnostic Pathology
Volume 10, Issue 4 , Pages 222-229, August 2006

Article Tools

* Image Usage & Resolution