Annals of Diagnostic Pathology
Volume 11, Issue 1 , Pages 46-48, February 2007

Paucicellular infiltrating ductal carcinoma of pancreas: an unusual variant

  • Mosa Fagih, MD, FRCPC
    • ,
  • Stefano Serra, MD
    • ,
  • Runjan Chetty, MB BCh, FRCPath, DPhil

      Affiliations

    • Corresponding Author InformationCorresponding author. Department of Pathology, Princess Margaret Hospital, Toronto, Ontario, Canada M5G 2M9. Fax: +1 416 946 6579.

Department of Pathology, University Health Network/Toronto Medical Laboratories, University of Toronto, Toronto, Canada M5G 2M9

Abstract 

A 65-year-old man presented with obstructive jaundice from a 3-cm mass in the head of the pancreas. A Whipple resection was performed. Histologic examination of the tumor showed scanty tumor cells arranged in a single-file manner set within a desmoplastic sclerotic stroma. In other areas, the tumor was arranged around preexisting ducts in a targetoid fashion. Very focal ductal and signet-ring cell differentiation was noted. This unusual variant of pancreatic cancer was characterized by paucicellularity and a pattern of invasion resembling lobular carcinoma of breast.

Keywords: Pancreas, Sclerosing cancer, Targetoid invasion

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PII: S1092-9134(05)00217-0

doi:10.1016/j.anndiagpath.2005.12.010

Annals of Diagnostic Pathology
Volume 11, Issue 1 , Pages 46-48, February 2007

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