Annals of Diagnostic Pathology
Volume 11, Issue 3 , Pages 217-219 , June 2007

Rectal stenosis caused by foreign body reaction to sodium polystyrene sulfonate crystals (Kayexalate)

  • Denis Chatelain, MD

      Affiliations

    • Department of Pathology, Centre Hospitalo-Universitaire Amiens, Place Victor Pauchet, 80054 Amiens Cedex 1, France
    • Corresponding Author InformationCorresponding author. Service d'Anatomie pathologique, CHU Amiens, Place Victor Pauchet, 80054 Amiens Cedex 01, France. Tel.: +33 3 22 66 84 40; fax: +33 3 22 66 84 87.
  • ,
  • Marie Brevet, MD

      Affiliations

    • Department of Pathology, Centre Hospitalo-Universitaire Amiens, Place Victor Pauchet, 80054 Amiens Cedex 1, France
  • ,
  • David Manaouil, MD

      Affiliations

    • Department of Digestive Surgery, Centre Hospitalo-Universitaire Amiens, Place Victor Pauchet, 80054 Amiens Cedex 1, France
  • ,
  • Thierry Yzet, MD

      Affiliations

    • Department of Radiology, Centre Hospitalo-Universitaire Amiens, Place Victor Pauchet, 80054 Amiens Cedex 1, France
  • ,
  • Jean-Marc Regimbeau, MD, PhD

      Affiliations

    • Department of Digestive Surgery, Centre Hospitalo-Universitaire Amiens, Place Victor Pauchet, 80054 Amiens Cedex 1, France
  • ,
  • Henri Sevestre, MD, PhD

      Affiliations

    • Department of Pathology, Centre Hospitalo-Universitaire Amiens, Place Victor Pauchet, 80054 Amiens Cedex 1, France

References 

  1. Abraham SC, Bhagavan BS, Lee LA, et al. Upper gastrointestinal tract injury in patients receiving Kayexalate (sodium polystyrene sulfonate) in sorbitol. Clinical, endoscopic and histopathological findings. Am J Surg Pathol. 2001;25:637–644
  2. Lillemoe KD, Romolo JL, Hamilton SR, et al. Intestinal necrosis due to sodium polystyrene (Kayexalate) in sorbitol enemas: clinical and experimental support for the hypothesis. Surgery. 1987;101:267–272
  3. Scott TR, Graham SM, Schweitzer EJ, et al. Colonic necrosis following sodium polystyrene sulfonate (Kayexalate)–sorbitol enema in a renal transplant patient. Report of a case and review of the literature. Dis Colon Rectum. 1993;36:607–609
  4. Rashid A, Hamilton SR. Necrosis of the gastrointestinal tract in uremic patients as a result of sodium polystyrene sulfonate (Kayexalate) in sorbitol. An underrecognized condition. Am J Surg Pathol. 1997;21:60–69
  5. Gardiner GW. Kayexalate (sodium polystyrene sulphonate) in sorbitol associated with intestinal necrosis in uremic patients. Can J Gastroenterol. 1997;11:573–577
  6. Dardik A, Moesinger RC, Efron G, et al. Acute abdomen with colonic necrosis induced by Kayexalate-sorbitol. South Med J. 2000;93:511–513
  7. Hernandez V, Hernandez IA, Berthrong M. Oleogranuloma simulating carcinoma of the rectum. Dis Colon Rectum. 1967;10:205–209
  8. Jung IS, Kim JO, Lee JS, et al. Barium granuloma of rectum diagnosed by EUS. Gastrointest Endosc. 2003;57:718–719
  9. Pereira TC, Prichard JW, Khalid M, et al. Rectal pulse granuloma. Arch Pathol Lab Med. 2000;125:822–823

PII: S1092-9134(06)00006-2

doi: 10.1016/j.anndiagpath.2006.02.001

Annals of Diagnostic Pathology
Volume 11, Issue 3 , Pages 217-219 , June 2007