Annals of Diagnostic Pathology
Volume 11, Issue 3 , Pages 223-227 , June 2007

Synovial sarcoma of the larynx in a 79-year-old woman, confirmed by karyotyping and fluorescence in situ hybridization analysis

  • Paulette Mhawech-Fauceglia, MD

      Affiliations

    • Department of Surgical Pathology and Laboratory Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 716 845 3204; fax: +1 716 845 3427.
    • ,
  • Peter Ramzy, MD

      Affiliations

    • Department of Head and Neck Surgery, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    • ,
  • Wiam Bshara, MD

      Affiliations

    • Department of Surgical Pathology and Laboratory Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    • ,
  • Sheila Sait, PhD

      Affiliations

    • Department of Surgical Pathology and Laboratory Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    • ,
  • Nestor Rigual, MD

      Affiliations

    • Department of Head and Neck Surgery, Roswell Park Cancer Institute, Buffalo, NY 14263, USA

References 

  1. Boniver V, Moreau P, Lefebvre Ph. Synovial sarcoma of the larynx: case report and literature review. B-ENT. 2005;1:47–51
  2. Papaspyrou S, Kyriakides G, Tapis M. Endoscopic CO2 laser surgery for large synovial sarcoma of the larynx. Otolaryngol Head Neck Surg. 2003;129:630–631
  3. Dei Tos AP, Sciot R, Giannini C, et al. Synovial sarcoma of larynx and hypopharynx. Ann Otol Rhinol Laryngol. 1998;107:1080–1085
  4. Quinn HJ. Synovial sarcoma of the larynx treated by partial laryngectomy. Laryngoscope. 1984;94:1158
  5. Morland B, Cox G, Randall C, Ramsay A, Rodford M. Synovial sarcoma of the larynx in a child. Med Pediatr Oncol. 1994;23:64–68
  6. Bilgic B, Mete O, Ozturk AS, Demiryont M, Keles N, Basaran M. Synovial sarcoma: a rare tumor of the larynx. Pathol Oncol Res. 2003;9:242–245
  7. Ferlito A, Caruso G. Endolaryngeal synovial sarcoma. An update on diagnosis and treatment. ORL. 1991;53:116–119
  8. Pruszcynski M, Manni JJ, Smedt F. Endolaryngeal synovial sarcoma: case report with immunohistochemical studies. Head and Neck. 1989;11:76–80
  9. Danninger R, Humer U, Stammberger H. Synovial sarcoma, a rare tumor of the larynx (case report and differential diagnostic consideration). Laryngo-Rhino-Otol. 1994;73:442–444
  10. Taylor SM, Ha D, Elluru R, El-Mofty S, Haughey B, Wallace M. Synovial sarcoma of the pericricoidal soft tissue. Otolaryngol Head Neck Surg. 2002;126:428–429
  11. Geahchan NE, Lambert J, Michau C, Richard JM. Malignant synovioma of the larynx. Ann Otolaryngol Chir cervicofac. 1983;100:61–65
  12. Amble FR, Olsen KD, Nascimento AG, Foote RL. Head and neck synovial cell sarcoma. Otolaryngol Head Neck Surg. 1992;107:631
  13. Ladanyi M. Fusions of the SYT and SSX genes in synovial sarcoma. Oncogene. 2001;20:5755–5762
  14. de Torres C, Cardesa TM, Rodriguez-Perales S, Cigudosa JC, Mora J. Epithelioid sarcoma with SYT-SSX1 fusion gene expression: molecular and cytogenetic analysis. Cancer Genet Cytogenet. 2005;162:50–56
  15. Ladanyi M, Antonescu CR, Leung DH, Woodruff JM, Kawai A, Healey JH, et al. Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients. Cancer Res. 2002;62:135–140
  16. Tassard M, Le D, Hacene K, et al. Prognostic factors in localized primary synovial sarcoma: a multicenter study of 128 adult patients. J Clin Oncol. 2001;19:525–534
  17. Kartha SS, Bumpous JM. Synovial cell sarcoma: diagnosis, treatment and outcomes. Laryngoscope. 2002;112(11):1979–1982

PII: S1092-9134(06)00009-8

doi: 10.1016/j.anndiagpath.2006.02.007

Annals of Diagnostic Pathology
Volume 11, Issue 3 , Pages 223-227 , June 2007

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