Annals of Diagnostic Pathology
Volume 12, Issue 2 , Pages 134-137, April 2008

Primary synovial sarcoma of the kidney: corroboration with in situ polymerase chain reaction

  • Fernando Gabilondo, MD

      Affiliations

    • Instituto Nacional de Nutrición y Ciencias Médicas Salvador Zubirán, Mexico City, Mexico
    • ,
  • Francisco Rodríguez, MD

      Affiliations

    • Instituto Nacional de Nutrición y Ciencias Médicas Salvador Zubirán, Mexico City, Mexico
    • ,
  • Alejandro Mohar, MD

      Affiliations

    • Instituto Nacional de Cancerología, Tlalpan, Mexico City, Mexico
    • ,
  • Gerald J. Nuovo, MD

      Affiliations

    • The Ohio State University Hospital, Columbus, OH, USA
    • ,
  • Hugo Domínguez-Malagón, MD

      Affiliations

    • Instituto Nacional de Cancerología, Tlalpan, Mexico City, Mexico
    • Corresponding Author InformationCorresponding author. Department of Pathology, Instituto Nacional de Cancerología, Ave San Fernando 22, Tlalpan, Mexico City DF 14080, Mexico. Tel.: +52 55 5628 0422; fax: +52 55 5628 0422.

published online 28 July 2007.

Abstract 

Synovial sarcoma is a tumor of the soft tissues with a unique chromosomal translocation t(X;18)(p 11.2;q11.2) that can be detected by polymerase chain reaction in tissue homogenates. The case of a 32-year-old woman with a primary synovial sarcoma of the kidney is described, the diagnosis was corroborated by the recently developed method of in situ polymerase chain reaction (IS-PCR). Synovial sarcoma of the kidney may be confused with other spindle cell tumors, for that reason IS-PCR may be useful to confirm the diagnosis in paraffin-embedded material.

Keywords: Synovial sarcoma, Kidney sarcomas, Spindle cell tumors of kidney

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PII: S1092-9134(06)00098-0

doi:10.1016/j.anndiagpath.2006.08.005

Annals of Diagnostic Pathology
Volume 12, Issue 2 , Pages 134-137, April 2008

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