Annals of Diagnostic Pathology
Volume 12, Issue 4 , Pages 267-270, August 2008

Eosinophilic angiocentric fibrosis of the sinonasal tract

  • Ognjen Kosarac, MD

      Affiliations

    • Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    • ,
  • Mario A. Luna, MD

      Affiliations

    • Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA
    • ,
  • Jae Y. Ro, MD, PhD

      Affiliations

    • Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    • ,
  • Alberto G. Ayala, MD

      Affiliations

    • Department of Pathology, The Methodist Hospital, Houston, TX 77030, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 713 441 1339; fax: +1 713 793 1603.

published online 04 October 2007.

Abstract 

Eosinophilic angiocentric fibrosis (EAF) is an uncommon inflammatory fibrosing lesion of the upper respiratory tract and orbit that occurs mainly in young to middle-aged women. The etiology of EAF is unknown. To our knowledge, approximately 28 cases have been previously reported in the English literature. We report here 3 additional cases of EAF of the sinonasal tract; 2 in women aged 19 and 31 years, and 1 in a man aged 49 years. The 19-year-old woman is the youngest patient with EAF ever described. The patients presented with a nasal cavity mass, face pain, or nasal obstructive symptoms of long duration.

Keywords: Eosinophilic angiocentric fibrosis, Nasal cavity, Onion-skin pattern

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PII: S1092-9134(07)00021-4

doi:10.1016/j.anndiagpath.2007.02.002

Annals of Diagnostic Pathology
Volume 12, Issue 4 , Pages 267-270, August 2008

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