Annals of Diagnostic Pathology
Volume 13, Issue 2 , Pages 114-118 , April 2009

Osteoclastlike giant cell tumor of the salivary gland

  • Xueping Fang, MD

      Affiliations

    • Department of Pathology, SUNY at Buffalo, Buffalo General Hospital, Buffalo, NY 14203, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 716 859 2140; fax: +1 716 859 1853.
  • ,
  • David G. Hicks, MD

      Affiliations

    • Department of Surgical Pathology and Laboratory Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
  • ,
  • Wesley Hicks Jr., MD

      Affiliations

    • Department of Head and Neck Surgery, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
  • ,
  • Shaozeng Zhang, MD

      Affiliations

    • Department of Surgical Pathology and Laboratory Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA

References 

  1. Eusebi V, Martin SA, Govoni E, et al. Giant cell tumor of major salivary glands: report of three cases, one occurring in association with a malignant mixed tumor. Am J Clin Pathol. 1984;8:666–675
  2. Tse LLY, Finkelstein SD, Siegler RW, et al. Osteoclast-type giant cell neoplasm of salivary gland. A microdissection-based comparative genotyping assay and literature review. Am J Surg Pathol. 2004;28(7):953–961
  3. Snyder ML, Paulino AF. Pathologic quiz case: an unusual salivary gland tumor. Arch Pathol Lab Med. 2000;124:1559–1560
  4. Donath K, Seifert G, Roser K. The spectrum of giant cells in tumors of the salivary glands: an analysis of 11 cases. J Oral Pathol Med. 1997;26:431–436
  5. Grenko RT, Tytor M, Boeryd B. Giant-cell tumor of the salivary gland with associated carcinosarcoma. Histopathol. 1993;23:594–595
  6. Itoh Y, Taniguti Y, Arai K. A case of giant cell tumor of the parotid gland. Ann Plast Surg. 1992;28:183–186
  7. Batsakis JG, Ordonez NG, Sevidal PA, et al. Osteoclast-type giant cell neoplasms of the parotid gland. J Laryngol Otol. 1988;102:901–904
  8. Balogh K, Wolbarsht RL, Federman M, et al. Carcinoma of the parotid gland with osteoclastlike giant cells. Immunohistochemical and ultrastructural observations. Arch Pathol Lab Med. 1985;109:756–761
  9. Ellis GL, Auclair PL, Gnepp DR. In: Surgical pathology of the salivary glands. Vol. 25:Philadelphia: WB Saunders; 1991;p. 490–509
  10. Gjerdrum LM, Lauridsen MC, Sorensen FB. Breast carcinoma with osteoclast-like giant cells: morphological and ultrastructural studies of a case with review of the literature. The Breast. 2001;10:231–236
  11. Imura J, Tomita S, Ono Y, et al. Endometrial adenosquamous carcinoma with osteoclast-like giant cells: immunohistochemistry and histogenesis. APMIS. 2005;113:140–144
  12. Orosz Z, Toth E, Viski A. Osteoclastoma-like giant cell tumor of the lung. Pathol Oncol Res. 1996;2(1-2):84–88
  13. Sakai Y, Kupelioglu AA, Yanagisawa A, et al. Origin of giant cells in osteoclast-like giant cell tumors of pancreas. Hum Pathol. 2000;31(10):1223–1229
  14. Heller KN, Manyak MJ, Tabbara SO, et al. Malignant osteoclast-like giant cell tumor of the kidney. Urology. 1998;51(3):495–498
  15. Teot LA, O'Keefe RJ, Rosier RN, et al. Extraosseous primary and recurrent giant cell tumors: transforming growth factor-β1 and -β2 expression may explain metaplastic bone formation. Hum Pathol. 1996;27(7):625–632
  16. Falini B, Flenghi L, Pileri S, et al. PG-M1: a new monoclonal antibody directed against a fixative-resistant epitope of the macrophage-restricted form of the CD 68 molecule. Am J Pathol. 1993;142:1359–1372
  17. O'Keefe RJ, Toet LA, Singh D, et al. Osteoclasts constitutively express regulators of bone resorption: an immunohistochemical and in situ hybridization study. Lab Invest. 1997;76(4):457–465

PII: S1092-9134(07)00102-5

doi: 10.1016/j.anndiagpath.2007.06.009

Annals of Diagnostic Pathology
Volume 13, Issue 2 , Pages 114-118 , April 2009