Annals of Diagnostic Pathology
Volume 12, Issue 1 , Pages 48-49, February 2008

Application of Tissue Microarrays in Placental Research☆

  • Lars-Christian Horn

      Affiliations

    • Division of Gynecologic and Perintatal Pathology, Institute of Pathology, University of Leipzig, D-04103 Leipzig, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 341 97 150 46; fax: +49 341 97 23 549.
    • ,
  • Sandra Purz

      Affiliations

    • Division of Gynecologic and Perintatal Pathology, Institute of Pathology, University of Leipzig, D-04103 Leipzig, Germany
    • Department of Obstetrics and Gynecology, University of Leipzig, D-04103 Leipzig, Germany
    • ,
  • Cornelia Leo

      Affiliations

    • Department of Obstetrics and Gynecology, University of Leipzig, D-04103 Leipzig, Germany
    • ,
  • Holger Stepan

      Affiliations

    • Department of Obstetrics and Gynecology, University of Leipzig, D-04103 Leipzig, Germany

Abstract 

A complementary tool to gene-based arrays are tissue microarrays, which allow the validation of DNA/RNA-derived profiling results on the protein level and offer the possibility of exact location within the tissue structures. Here we describe the technical details of the application of tissue microarray in placental research. Although the placenta represents a very inhomogeneous organ, this technique is also usable in placental research.

Keywords: Tissue microarray, Placenta, Immunohistochemistry, Translational research

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☆ There are no financial relationships between the authors and commercial companies whose products are mentioned in the text.

PII: S1092-9134(07)00124-4

doi:10.1016/j.anndiagpath.2007.08.004

Annals of Diagnostic Pathology
Volume 12, Issue 1 , Pages 48-49, February 2008

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