Annals of Diagnostic Pathology
Volume 13, Issue 4 , Pages 278-284 , August 2009

Dedifferentiated liposarcoma with peculiar meningothelial-like whorling and metaplastic bone formation

  • Joon Seon Song, MD

      Affiliations

    • Department of Pathology, Weill Medical College of Cornell University, The Methodist Hospital, Houston, TX 77030, USA
    • Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, Korea
    • ,
  • Jerad M. Gardner, MD

      Affiliations

    • Department of Pathology, Weill Medical College of Cornell University, The Methodist Hospital, Houston, TX 77030, USA
    • ,
  • William P. Tarrant, MD

      Affiliations

    • Department of Pathology, Weill Medical College of Cornell University, The Methodist Hospital, Houston, TX 77030, USA
    • ,
  • Steven Shen, MD, PhD

      Affiliations

    • Department of Pathology, Weill Medical College of Cornell University, The Methodist Hospital, Houston, TX 77030, USA
    • ,
  • Alberto G. Ayala, MD

      Affiliations

    • Department of Pathology, Weill Medical College of Cornell University, The Methodist Hospital, Houston, TX 77030, USA
    • ,
  • Eunsil Yu, MD, PhD

      Affiliations

    • Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, Korea
    • ,
  • Jae Y. Ro, MD, PhD

      Affiliations

    • Department of Pathology, Weill Medical College of Cornell University, The Methodist Hospital, Houston, TX 77030, USA
    • Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138-736, Korea
    • Corresponding Author InformationCorresponding author. Department of Pathology, Weill Medical College of Cornell University, The Methodist Hospital, Houston, TX 77030, USA. Tel.: +1 713 441 2263; fax: +1 713 793 1603.

References 

  1. Evans HL. Liposarcoma: a study of 55 cases with a reassessment of its classification. Am J Surg Pathol. 1979;3:507–523
  2. Weiss SW, Rao VK. Well-differentiated liposarcoma (atypical lipoma) of deep soft tissue of the extremities, retroperitoneum, and miscellaneous sites. A follow-up study of 92 cases with analysis of the incidence of “dedifferentiation”. Am J Surg Pathol. 1992;16:1051–1058
  3. Evans HL, Khurana KK, Kemp BL, et al. Heterologous elements in the dedifferentiated component of dedifferentiated liposarcoma. Am J Surg Pathol. 1994;18:1150–1157
  4. McCormick D, Mentzel T, Beham A, et al. Dedifferentiated liposarcoma. Clinicopathologic analysis of 32 cases suggesting a better prognostic subgroup among pleomorphic sarcomas. Am J Surg Pathol. 1994;18:1213–1223
  5. Henricks WH, Chu YC, Goldblum JR, et al. Dedifferentiated liposarcoma: a clinicopathological analysis of 155 cases with a proposal for an expanded definition of dedifferentiation. Am J Surg Pathol. 1997;21:271–281
  6. Fanburg-Smith JC, Miettinen M. Liposarcoma with meningothelial-like whorls: a study of 17 cases of a distinctive histological pattern associated with dedifferentiated liposarcoma. Histopathology. 1998;33:414–424
  7. Nascimento AG, Kurtin PJ, Guillou L, et al. Dedifferentiated liposarcoma: a report of nine cases with a peculiar neurallike whorling pattern associated with metaplastic bone formation. Am J Surg Pathol. 1998;22:945–955
  8. Liu D, Quinonez G, Latosinsky S. Dedifferentiated liposarcoma with a paraganglioma-like histologic pattern: a case report and review of the literature. Arch Pathol Lab Med. 2004;128:788–791
  9. Hasegawa T, Seki K, Hasegawa F, et al. Dedifferentiated liposarcoma of retroperitoneum and mesentery: varied growth patterns and histological grades—a clinicopathologic study of 32 cases. Hum Pathol. 2000;31:717–727
  10. Kim SH, Choi YJ, Kim HJ, et al. Liposarcoma with meningothelial-like whorls. Report of four cases showing diverse histologic findings and behavior. Yonsei Med J. 2003;44:392–400
  11. Matsumoto T, Fukunaga M, Fujii H, et al. Inguinal dedifferentiated liposarcoma with meningothelial-like whorls and metaplastic bone formation. Histopathology. 2005;46:594–596
  12. Macarenco RS, Erickson-Johnson M, Wang X, et al. Cytogenetic and molecular cytogenetic findings in dedifferentiated liposarcoma with neural-like whorling pattern and metaplastic bone formation. Cancer Genet Cytogenet. 2007;172:147–150
  13. Fletcher CD, Akerman M, Dal Cin P, et al. Correlation between clinicopathological features and karyotype in lipomatous tumors. A report of 178 cases from the Chromosomes and Morphology (CHAMP) Collaborative Study Group. Am J Pathol. 1996;148:623–630
  14. DeiTos AP, Pedeutour F. Dedifferentiated liposarcoma. In:  Fletctcher CDM editors. Pathology and genetics; tumors of soft tissue and bone. Lyon, France: IARCPress; 2002;p. 38–39

PII: S1092-9134(08)00079-8

doi: 10.1016/j.anndiagpath.2008.07.002

Annals of Diagnostic Pathology
Volume 13, Issue 4 , Pages 278-284 , August 2009

Article Tools

* Image Usage & Resolution