Annals of Diagnostic Pathology
Volume 14, Issue 5 , Pages 358-360, October 2010

Perianal mammary-type myofibroblastoma

  • Yaxia Zhang, MD, PhD

      Affiliations

    • Department of Pathology, University of Miami Miller School of Medicine/JMH, Miami, FL 33136, USA
    • ,
  • Merce Jorda, MD, PhD

      Affiliations

    • Department of Pathology, University of Miami Miller School of Medicine/JMH, Miami, FL 33136, USA
    • Corresponding Author InformationCorresponding author. Jackson Memorial Hospital, UM, Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA.
    • ,
  • John R. Goldblum, MD

      Affiliations

    • Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH 44195, USA

published online 09 December 2009.

Abstract 

We report a unique case of an extramammary mammary-type myofibroblastoma of the perianal region. The patient was a 40-year old female with no significant past history, who presented with a right side painless perianal mass. Gross examination of the excised mass showed a well-circumscribed, apparently encapsulated, nodular mass weighing 30 g and measuring 5 cm. in the greatest dimension. The cut surface showed solid, yellow homogenous tissue. Microscopically, the neoplasm was composed of bland spindled cells generally arranged into short fascicles with abundant myxoid stroma. The cells stained strongly for desmin and CD34. To our knowledge, a review of the literature discloses only ten cases of extramammary, mammary-type myofibroblastoma.

Keywords: Perianal, Mammary-type myofibroblastoma, Desmin, CD34

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PII: S1092-9134(09)00119-1

doi:10.1016/j.anndiagpath.2009.08.005

Annals of Diagnostic Pathology
Volume 14, Issue 5 , Pages 358-360, October 2010

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