Annals of Diagnostic Pathology
Volume 14, Issue 3 , Pages 178-181, June 2010

Primary myxoma of the lung

  • Neda Kalhor, MD

      Affiliations

    • Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1 713 792 2642; fax: +1 713 563 1848.
    • ,
  • Edith M. Marom, MD

      Affiliations

    • Department of Diagnostic Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    • ,
  • Cesar A. Moran, MD

      Affiliations

    • Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA

published online 21 December 2009.

Abstract 

A case of primary myxoma of the lung is presented. The patient is a 70-year-old woman who presented with a history of dyspnea, cough, and mild chest discomfort. Chest radiographic studies disclosed the presence of a well-marginated nodule in the left upper lobe. A wedge resection of the tumor mass was performed. The specimen contained a tan-gray, soft, well-circumscribed tumor nodule of approximately 1.8 cm in greatest dimension. Histologically, the tumor was characterized by a well-demarcated lesion, composed of loose spindle and stellate cells embedded in a myxoid matrix, containing thin-walled vessels. Immunohistochemical studies showed the cell to be negative for S-100, keratin, desmin, smooth muscle actin, and HMB-45. Vimentin stain showed positive staining in some of the stellate cells. No evidence of recurrence or metastatic disease was observed after 18 months.

Keywords: Lung, Myxoma

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PII: S1092-9134(09)00120-8

doi:10.1016/j.anndiagpath.2009.09.009

Annals of Diagnostic Pathology
Volume 14, Issue 3 , Pages 178-181, June 2010

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