Annals of Diagnostic Pathology
Volume 14, Issue 5 , Pages 321-327 , October 2010

Prognostic significance of vascular endothelial growth factor, basic fibroblastic growth factor, and microvessel density and their relation to cell proliferation in B-cell non-Hodgkin's lymphoma

References 

  1. Koster A, van Krieken JH, Mackenzie MA, et al. Increased vascularization predicts favorable outcome in follicular lymphoma. Clin Cancer Res. 2005;11:154–161
  2. Francesco B, Lisa F, Patrizia M, et al. Endostatin, an antiangiogenic drug, induces tumor stabilization after chemotherapy or anti-CD20 therapy in a NOD/SCID mouse model of human high-grade non-Hodgkin lymphoma. Blood. 2000;
  3. Salven P, Orpana A, Teerenhovi L, et al. Simultaneous elevation in the serum concentrations of the angiogenic growth factors VEGF and bFGF is an independent predictor of poor prognosis in non-Hodgkin lymphoma: a single-institution study of 200 patients. Blood. 2000;96:3712–3718
  4. Mangi MH, Newland AC. Angiogenesis and angiogenic mediators in hematological malignancies. Br J Haematol. 2000;111:43–51
  5. Scappaticci FA. Mechanisms and future directions for angiogenesis-based cancer therapies. J Clin Oncol. 2002;20:3906–3927
  6. Eunice S, Julie T, Yan W, et al. Targeting autocrine and paracrine VEGF receptor pathways inhibits human lymphoma xenografts in vivo. Blood. 2004;104:2893–2902
  7. Jia R, Elizabeth H, Pouneh K, et al. Magnitude of stromal hemangiogenesis correlates with histologic subtype of non-Hodgkin's lymphoma. In: AACR-NCI-EORTC international conference. Molecular targets and cancer therapeutics. Boston, MA, Nov 15-19. 2009;
  8. William T, Lynne R, Yvette F, et al. Expression of vascular endothelial growth factor and its receptors in hematopoietic malignancies. Cancer Res. 1999;59:728–733
  9. Ribatti D, Vacca A, Nico B, et al. Angiogenesis spectrum in the stroma of B-cell non-Hodgkin's lymphomas. An immunohistochemical and ultrastructural study. Eur J Haematol. 1996;56:45–53
  10. Perez-Atayde AR, Sallan SE, Tedrow U, et al. Spectrum of tumor angiogenesis in the bone marrow of children with acute lymphoblastic leukemia. Am J Pathol. 1997;150:815–821
  11. Dita G, Shuchun Z, Robert J, et al. Microvessel density and expression of vascular endothelial growth factor and its receptors in diffuse large B-cell lymphoma subtypes. Am J Pathol. 2007;170:1362–1369
  12. Petri S, Lasse T, Heikki J. A high pretreatment serum basic fibroblast growth factor concentration is an independent predictor of poor prognosis in non-Hodgkin's lymphoma. Blood. 1999;94:3334–3339
  13. Pazga I, Zimra Y, Tzabar C, et al. Expression of basic fibroblast growth factor is associated with poor outcome in non-Hodgkin's lymphoma. Br J Cancer. 2002;86:1770–1775
  14. Juczewska M, Chyczewska E, Naumnik W, et al. Endothelial cells and angiogenesis intensity in lung cancer. Folia Histochem Cytobiol. 2001;39:253–258
  15. Wróbel T, Mazur G, Surowiak P, Dzie Giel P, et al. Increased expression of vascular endothelial growth factor (VEGF) in bone marrow of multiple myeloma (MM) patients. Eur J Int Med. 2003;14:98–100
  16. Usnarska-Zubkiewicz L, Mazur G, Wróbel T, et al. Expression of serum vascular endothelial growth factor correlates with clinical outcome in multiple myeloma (in Polish). Pol Arch Med Wewn. 2003;110:719–724
  17. Grzegorz M, Tomasz W, Piotr D, et al. Angiogenesis measured by expression of CD34 antigen in lymph nodes of patients with non Hodgkin's lymphoma. Folia Histochem Cytobiol. 2004;42:241–243
  18. Poon RT, Fan ST, Wong J. Clinical implications of circulating angiogenic factors in cancer patients. J Clin Oncol. 2001;19:1207–1225
  19. Harris NL, Jaffe ES, Diebold J. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee Meeting, Airline House, Virginia. J Clin Oncol. 1999;17:3835–3849
  20. Lister TA, Crowdther D. Staging for Hodgkin's disease. Semin Oncol. 1990;17:696–703
  21. Yiangou C, Gomm JJ, Coope RC. Fibroblast growth factor 2 in breast cancer: occurrence and prognostic significance. Br J Cancer. 1997;75:28–33
  22. Nardone G, Staibano S, Rocco A, et al. Effect of Helicobacter pylori infection and its eradication on cell proliferation, DNA status, and oncogene expression in patients with chronic gastritis. Gut. 1999;44:789–799
  23. Ribatti D, Vacca A, Marzullo A. Angiogenesis and mast cell density with tryptase activity increase simultaneously with pathological progression in B-cell non-Hodgkin's lymphomas. Int J Cancer. 2000;15:171–175
  24. Ho CL, Sheu LF, Li CY. Immunohistochemical expression of basic fibroblast growth factor, vascular endothelial growth factor, and their receptors in stage IV non-Hodgkin lymphoma. Appl Immunohistochem Mol Morphol. 2002;10:316–321
  25. Berthold SMD, Andreas CMD, Daniela H, et al. Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas. N Engl J Med. 2004;351:250–259
  26. Yamazaki K, Nagao T, Yamaguchi T, et al. Expression of basic fibroblast growth factor (FGF-2)-associated with tumor proliferation in human pancreatic carcinoma. Virchow Arch. 1997;431:95–101
  27. Blanckaert VD, Hebbar M, Louchez MM, et al. Basic fibroblast growth factor receptors and their prognostic value in human breast cancer. Clin Cancer Res. 1998;4:2939–2947
  28. Menzel T, Rahman Z, Calleja E, et al. Elevated intracellular level of basic fibroblast growth factor correlates with stage of chronic lymphocytic leukemia and is associated with resistance to fludarabine. Blood. 1996;87:1056–1063
  29. Gruber G, Schwarzmeier JD, Shehata M, et al. Basic fibroblast growth factor is expressed by CD19/CD11c-positive cells in hairy cell leukemia. Blood. 1999;94:1077–1085
  30. Sezer O, Jakob C, Eucker J, et al. Serum levels of the angiogenic cytokines basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in multiple myeloma. Eur J Haematol. 2001;66:83–88
  31. Ridell B, Norrby K. Intratumoral microvascular density in malignant lymphomas of B-cell origin. APMIS. 2001;109:66–72
  32. Arias V, Soares FA. Vascular density (tumor angiogenesis) in non-Hodgkin's lymphomas and florid follicular hyperplasia: a morphometric study. Leuk Lymphoma. 2000;40:157–166
  33. Kumar S, Gertz MA, Dispenzieri A, et al. Prognostic value of bone marrow angiogenesis in patients with multiple myeloma undergoing high-dose therapy. Bone Marrow Transplant. 2004;34:235–239

PII: S1092-9134(09)00172-5

doi: 10.1016/j.anndiagpath.2009.12.011

Annals of Diagnostic Pathology
Volume 14, Issue 5 , Pages 321-327 , October 2010