Annals of Diagnostic Pathology
Volume 15, Issue 4 , Pages 282-285 , August 2011

Clear cell papillary renal cell carcinoma and clear cell renal cell carcinoma arising in acquired cystic disease of the kidney: an immunohistochemical and genetic study

  • Naoto Kuroda, MD

      Affiliations

    • Department of Diagnostic Pathology, Kochi Red Cross Hospital, Kochi, Japan
    • Corresponding Author InformationCorresponding author. Tel.: +81 88 822 1201; fax: +81 88 822 1056.
    • ,
  • Tomoyuki Shiotsu, MD

      Affiliations

    • Department of Urology, Kochi Red Cross Hospital, Kochi, Japan
    • ,
  • Chiaki Kawada, MSc

      Affiliations

    • Department of Urology, Kochi Medical School, Kochi University, Kochi, Japan
    • ,
  • Taro Shuin, MD

      Affiliations

    • Department of Urology, Kochi Medical School, Kochi University, Kochi, Japan
    • ,
  • Ondrej Hes, MD

      Affiliations

    • Department of Pathology, Charles University Hospital Plzen, Plzen, Czech Republic
    • ,
  • Michal Michal, MD

      Affiliations

    • Department of Pathology, Charles University Hospital Plzen, Plzen, Czech Republic
    • ,
  • Chisato Ohe, MD

      Affiliations

    • Department of Pathology, Kansai Medical University Hirakata Hospital, Osaka, Japan
    • ,
  • Shuji Mikami, MD

      Affiliations

    • Division of Diagnostic Pathology, Keio University Hospital, Tokyo, Japan
    • ,
  • Chin-Chen Pan, MD

      Affiliations

    • Department of Pathology, Taipei Veterans General Hospital, Taipei, Taiwan

References 

  1. Tickoo SK, Mariza N, dePeralta-Venturina MN, et al. Spectrum of epithelial neoplasms in end-stage renal disease. An experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. Am J Surg Pathol. 2006;30:141–153
  2. Gobbo S, Eble JN, Grignon DJ, et al. Clear cell papillary renal cell carcinoma. A distinct histopathologic and molecular genetic entity. Am J Surg Pathol. 2008;32:1239–1245
  3. Ashida S, Nishimori I, Tanimura M, et al. Effects of von Hippel–Lindau gene mutation and methylation status on expression of transmembrane carbonic anhydrases in renal cell carcinoma. J Cancer Res Clin Oncol. 2002;128:561–566
  4. Kuroda N, Tamura M, Shiotsu T, et al. Chromosomal abnormalities of clear cell renal cell carcinoma: frequent incidence of gain of chromosome 7. Pathol Int. 2010;60:9–13
  5. Kovacs G. Papillary renal cell carcinoma. A morphologic and cytogenetic study of 11 cases. Am J Pathol. 1989;134:27–34
  6. Kovacs G, Fuzesi L, Emanuel A, et al. Cytogenetics of papillary renal cell tumors. Genes Chromosomes Cancer. 1991;3:249–255
  7. Kattar MM, Grignon DJ, Wallis T, et al. Clinicopathologic and interphase cytogenetic analysis of papillary (chromophilic) renal cell carcinoma. Mod Pathol. 1997;10:1143–1150
  8. Delahunt B, Eble JN. Papillary renal cell carcinoma: a clinicopathologic and immunohistochemical study of 105 cases. Mod Pathol. 1997;10:537–544
  9. Sanders ME, Mick R, Tomaszewski JE, et al. Unique patterns of allelic imbalance distinguish type 1 from type 2 sporadic papillary renal cell carcinoma. Am J Pathol. 2002;161:997–1005
  10. Yang J, Tan MH, Kim HL, et al. A molecular classification of papillary renal cell carcinoma. Cancer Res. 2005;65:5628–5637
  11. Lefevre M, Couturier J, Sibony M, et al. Adult papillary renal tumor with oncocytic cells. Clinicopathologic, immunohistochemical, and cytogenetic features of 10 cases. Am J Surg Pathol. 2005;29:1576–1581
  12. Hes O, Brunelli M, Michal M, et al. Oncocytic papillary renal cell carcinoma: a clinicopathologic, immunohistochemical, ultrastructural, and interphase cytogenetic study of 12 cases. Ann Diagn Pathol. 2006;10:133–139
  13. Fuzesi L, Gunawan B, Bergmann F, et al. Papillary renal cell carcinoma with clear cell cytomorphology and chromosomal loss of 3p. Histopathology. 1999;35:157–161
  14. Salama ME, Worsham MJ, DePeralta-Venturina M. Malignant papillary renal tumors with extensive clear cell change. Arch Pathol Lab Med. 2003;127:1176–1181
  15. Gobbo S, Eble JN, MacLennan GT, et al. Renal cell carcinomas with papillary architecture and clear cell components. The utility of immunohistochemical and cytogenetical analyses in differential diagnosis. Am J Surg Pathol. 2008;32:1780–1786

PII: S1092-9134(10)00044-4

doi: 10.1016/j.anndiagpath.2010.03.007

Annals of Diagnostic Pathology
Volume 15, Issue 4 , Pages 282-285 , August 2011

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