Annals of Diagnostic Pathology
Volume 14, Issue 5 , Pages 341-346 , October 2010

Cystic paraganglioma of the anterior mediastinum

  • Pablo F. Ortega, MD

      Affiliations

    • Department of Pathology and Laboratory Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
  • ,
  • Luis Antonio Sosa, MD

      Affiliations

    • Department of Radiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
  • ,
  • Manan Patel, MD

      Affiliations

    • Pathology Laboratory, ProHealth Care, Waukesha, WI 53188, USA
  • ,
  • Eduardo Zambrano, MD

      Affiliations

    • Department of Pathology and Laboratory Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    • Corresponding Author InformationCorresponding author.

References 

  1. Maier HC. Intrathoracic pheochromocytoma with hypertension. Ann Surg. 1949;130(6):1059–1065[illust]
  2. Rachid H, El Biaze M, Yassine N, et al. Mediastinal paraganglioma with pleural metastasis. A case report. Rev Pneumol Clin. 2005;61(5 Pt 1):315–318
  3. Lamy AL, Fradet GJ, Luoma A, Nelems B. Anterior and middle mediastinum paraganglioma: complete resection is the treatment of choice. Ann Thorac Surg. 1994;57(1):249–252
  4. Paul S, Jain SH, Gallegos RP, Aranki SF, Bueno R. Functional paraganglioma of the middle mediastinum. Ann Thorac Surg. 2007;83(6):e14–e16
  5. Evans RW. Histological appearances of tumours with a consideration of their histogenesis and certain aspects of their clinical features and behaviour. 2nd ed.. Edinburgh (London): E. & S. Livingstone; 1966;
  6. Glenner GG, Grimley PM. Tumors of the extra-adrenal paraganglion system (including chemoreceptors). Washington: Armed Forces Institute of Pathology; for sale by the American Registry of Pathology, Armed Forces Institute of Pathology; 1974;
  7. Kliewer KE, Cochran AJ. A review of the histology, ultrastructure, immunohistology, and molecular biology of extra-adrenal paragangliomas. Arch Pathol Lab Med. 1989;113(11):1209–1218
  8. Moran CA, Suster S, Fishback N, Koss MN. Mediastinal paragangliomas. A clinicopathologic and immunohistochemical study of 16 cases. Cancer. 1993;72(8):2358–2364
  9. Carney JA. The triad of gastric epithelioid leiomyosarcoma, functioning extra-adrenal paraganglioma, and pulmonary chondroma. Cancer. 1979;43(1):374–382
  10. Ghayee HK, Havekes B, Corssmit EP, et al. Mediastinal paragangliomas: association with mutations in the succinate dehydrogenase genes and aggressive behavior. Endocr Relat Cancer. 2009;16(1):291–299
  11. Marchevsky AM, Kaneko M. Surgical pathology of the mediastinum. 2nd ed.. New York: Raven Press; 1992;
  12. Suster S, Rosai J. Multilocular thymic cyst: an acquired reactive process. Study of 18 cases. Am J Surg Pathol. 1991;15(4):388–398
  13. Suster S, Barbuto D, Carlson G, Rosai J. Multilocular thymic cysts with pseudoepitheliomatous hyperplasia. Hum Pathol. 1991;22(5):455–460
  14. Mortman KD. Mediastinal thoracic duct cyst. Ann Thorac Surg. 2009;88(6):2006–2008
  15. Kabiri el H, al Aziz S, el Maslout A, Benosman A. Hydatid cyst: an unusual disease of the mediastinum. Acta Chir Belg. 2001;101(6):283–286
  16. Suster S, Rosai J. Cystic thymomas. A clinicopathologic study of ten cases. Cancer. 1992;69(1):92–97
  17. Moran CA, Suster S. Thymoma with prominent cystic and hemorrhagic changes and areas of necrosis and infarction: a clinicopathologic study of 25 cases. Am J Surg Pathol. 2001;25(8):1086–1090
  18. Moran CA, Suster S. Mediastinal seminomas with prominent cystic changes. A clinicopathologic study of 10 cases. Am J Surg Pathol. 1995;19(9):1047–1053
  19. Moran CA, Suster S. Mediastinal yolk sac tumors associated with prominent multilocular cystic changes of thymic epithelium: a clinicopathologic and immunohistochemical study of five cases. Mod Pathol. 1997;10(8):800–803
  20. Kamiya N, Yokoi K, Mori K, Tominaga K, Miyazawa N. Thymic Hodgkin's disease with cystic variants: a case report. Nihon Kyobu Shikkan Gakkai Zasshi. 1995;33(9):999–1002
  21. Moran CA, Suster S, Silva EG. Low-grade serous carcinoma of the ovary metastatic to the anterior mediastinum simulating multilocular thymic cysts: a clinicopathologic and immunohistochemical study of 3 cases. Am J Surg Pathol. 2005;29(4):496–499
  22. Lee TH, Slywotzky CM, Lavelle MT, Garcia RA. Cystic pheochromocytoma. Radiographics. 2002;22(4):935–940
  23. Klingler PJ, Fox TP, Menke DM, Knudsen JM, Fulmer JT. Pheochromocytoma in an incidentally discovered asymptomatic cystic adrenal mass. Mayo Clin Proc. 2000;75(5):517–520
  24. Rozenblit A, Morehouse HT, Amis ES. Cystic adrenal lesions: CT features. Radiology. 1996;201(2):541–548
  25. Balcombe J, Torigian DA, Kim W, Miller WT. Cross-sectional imaging of paragangliomas of the aortic body and other thoracic branchiomeric paraganglia. AJR Am J Roentgenol. 2007;188(4):1054–1058
  26. Kim Y, Lee KS, Yoo JH, et al. Middle mediastinal lesions: imaging findings and pathologic correlation. Eur J Radiol. 2000;35(1):30–38
  27. Wald O, Shapira OM, Murar A, Izhar U. Paraganglioma of the mediastinum: challenges in diagnosis and surgical management. J Cardiothorac Surg. 2010;5(1):19
  28. Sahdev A, Sohaib A, Monson JP, Grossman AB, Chew SL, Reznek RH. CT and MR imaging of unusual locations of extra-adrenal paragangliomas (pheochromocytomas). Eur Radiol. 2005;15(1):85–92
  29. Lack EE, Stillinger RA, Colvin DB, Groves RM, Burnette DG. Aortico-pulmonary paraganglioma: report of a case with ultrastructural study and review of the literature. Cancer. 1979;43(1):269–278
  30. Namba R, Saika Y, Nakata Y, et al. A case of benign paraganglioma arising in the middle mediastinum; 201Tl-SPECT for differentiation from malignant tumor. Kaku Igaku. 1993;30(9):1097–1101

PII: S1092-9134(10)00067-5

doi: 10.1016/j.anndiagpath.2010.04.008

Annals of Diagnostic Pathology
Volume 14, Issue 5 , Pages 341-346 , October 2010